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| Section | Objectives |
|---|---|
| Part I: Knowledge-Based Assessment | - Foundational pharmacotherapy knowledge
|
| Part II: Applied Clinical Decision Making | - Case-based pharmacotherapy scenarios
|
| Special Populations | - Pediatrics and geriatrics
|
| Disease State Management | - Infectious diseases
|
| Patient Care and Pharmacotherapy Principles | - Therapeutic decision making
|
1. A 25-year-old woman who is HIV-positive and has a CD4+ count of 120 cells/mm begins antiretroviral therapy. The patient's CD4+ count drops to 45 cells/mm3 over the next year. For which of the following opportunistic infections should this patient receive prophylaxis?
A) Mycobacterium tuberculosis and Pneumocystis Jirovecii pneumonia
B) Mycobacterium tuberculosis and CMV
C) MAC and Pneumocystis jirovecii pneumonia
D) MAC and Candida
2. A 72-year-old patient, weighing 72 kg and measuring 173 cm tall, presents to the emergency department with an acute ischemic stroke. The symptoms have been present for just over an hour. The patient has a history of hypertension and is currently taking lisinopril 10 mg daily.
The patient's evaluation reveals no intracerebral hemorrhaging. The current BP is 178/100 mm Hg. It is now 150 minutes from stroke symptom onset.
Which of the following should now be administered?
A) Intravenous-PA
B) An antihypertensive; reconsider intra-arterial thrombolytics once BP decreases
C) Intravenous glycoprotein IIb/IIIa inhibitor
D) An antihypertensive; reconsider intravenous t-PA once BP decreases
3. Permission to use a previously published figure or illustration in a manuscript should be initially obtained from which of the following?
A) The editor of the journal to which the manuscript is being submitted
B) The National Library of Medicine
C) The author of the original article
D) The publisher of the journal or book containing the original figure
4. A patient is started on ledipasvir-sofosbuvir. What would be the best indicator of treatment response?
A) Absence of cryoglobulinemia
B) Absence of alpha-fetoprotein
C) HCV RNA below the lower limit of quantification
D) ALT less than three times the upper limit of normal
5. A patient with hepatic encephalopathy is being treated with lactulose 15 mL four times daily.
Over the next 72 hours, the patient becomes less agitated but remains disoriented. Which of the following should be the next step?
A) Measure stool pH to ensure that it is greater than 7.
B) Determine the frequency of bowel movements.
C) Begin branched-chain amino-acid supplementation.
D) Add neomycin 1 g four times daily.
Solutions:
| Question # 1 Answer: C | Question # 2 Answer: A | Question # 3 Answer: C | Question # 4 Answer: C | Question # 5 Answer: D |
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